CZechMS.org - CMSC 2024

CMSC 2024 - Program

Wednesday October 30, 2024

10:00 - 17:30 Registration
13:00 - 13:20 Conference opening
13:20 - 14:10 Plenary lecture I: Prof. Wolfram Weckwerth (Universität Wien)
PL-01: Metabolomics, the Panome and AI-Based Metabolic Modelling – applications in Immunometabolism, Cancer and Natural Product Treatment
14:10 - 15:40 Session I (Chairperson: Zdeněk Kukačka)
- 14:10 - 14:30 Zdeněk Kameník
  WeO-01: Functional Group Molecular Networking (FunMN) Applied to Mouse Gut Microbiota-Associated Polar Metabolites
- 14:30 - 14:50 Kateřina Grabicová
  WeO-02: Brown trout exposed to WWTP discharge - bioaccumulation and metabolome
- 14:50 - 15:10 Petr Žáček
  WeO-03: Comprehensive two-dimensional gas chromatography with mass spectrometric detection (GCxGC-TOF/MS) is a powerful tool for untargeted metabolomics
- 15:10 - 15:40 Hamish Stewart
  WeO-04: Orbitrap Astral and Stellar mass spectrometers, new stars for discovery and targeted analysis
15:40 - 16:00 Coffee break
16:00 - 16:40 Workshop Pragolab (Dr. Hamish Stewart: The journey to the Astral analyzer)
16:40 - 17:30 Poster talks (Chairperson: Anton Škríba)
- Tomáš Korba
  WeS-01: Removing contaminating ions in Q0 region to increase robustness of MS analyzer
- Pavla Fialová
  WeS-02: Mapping Chemical Space Sampled by Three Passive Samplers in Wastewater Effluent Using LC-HRMS and Suspect Screening
- Alina Sadchenko
  WeS-03: Assessing Pesticide Levels in Soils of the Czech Republic: Methods and Findings
- Jana Schwarzerová
  WeS-04: Transitioning from User-Based Applications to Cloud Computing: The Python-Based COVAIN v2.0 Toolbox for Metabolomics Data Analysis on Google Colab
- Michal Jágr
  WeS-05: Comprehensive study of the effect of oat grain germination on the content of avenanthramides
- Marek Zákopčáník / Dmitry Loginov
  WeS-06: Peptide Identification framework for Fast Photochemical Oxidation of Proteins
- Michal Baka
  WeS-07: Ion Exchange Trapping: A Solution for Excess Derivatization Reagent Removal
17:40 - 23:00 Drinks and poster session (live music from 19:30)

Thursday October 31, 2024

09:00 - 09:50 Plenary lecture II: Dr. Robert Mistrík (Bitmoderna, s.r.o.)
PL-02: mzCloud – 10 Years Striving for Perfection
09:50 - 10:50 Session II (Chairperson: Petr Šimek)
- 09:50 - 10:10 Jan Fiala
  ThO-05: Protein-Centric Antibody Repertoire Profiling on timsTOF: Pioneering Insights into Sensitivity and Characterization
- 10:10 - 10:30 Summra Ahmed
  ThO-06: Microbial Siderophores Intercalated into Lipocalin-1: Native Mass Spectrometry and Molecular Modelling
- 10:30 - 10:50 Vítězslav Brinsa
  ThO-07: Utilizing the native MS to study protein-DNA binding modes
10:50 - 11:10 Coffee break
11:10 - 13:00 Session III (Chairperson: Kristýna Gloc Pimková)
- 11:10 - 11:40 Goran Mitulovic
  ThO-08: No throughput/sensitivity compromises with 4-D proteomics at PASEF speed: Current and upcoming applications for deeper insights
- 11:40 - 12:00 Peter Konik
  ThO-09: Profiling protein expression in Synechocystis using quantitative proteomics
- 12:00 - 12:20 Tomáš Ječmen
  ThO-10: NKp46 receptor O-glycoprofiling by bottom-up proteomics using recently discovered O glycoprotease
- 12:20 - 12:40 Tereza Kozelková
  ThO-11: Proteomic insight into the midgut of the hard tick Ixodes ricinus with the special focus on the lipolytic system
- 12:40 - 13:00 Zuzana Kalaninová
  ThO-12: Post-proline Cleaving Enzymes in the Spotlight: Exploring the Hidden Specificity
13:00 - 14:00 Lunch
14:00 - 15:00 Session IV (Chairperson: Zdeněk Spáčil)
- 14:00 - 14:20 Roman Grabic
  ThO-13: Can we find unknown unknowns? LC-HRMS DIA or DDA? That is the question.
- 14:20 - 14:40 Alžběta Nemeškalová
  ThO-14: Ambient ionization mass spectrometry provides screening of performance-enhancing drugs in clandestine products
- 14:40 - 15:00 Filip Gregar
  ThO-15: Ultraviolet LAESI/LAESCI: a novel approach for ambient MSI
15:00 - 15:30 prof. Zdeněk Herman award lecture: Lukáš Tomaník
ThO-16: Photoemission spectroscopy of liquids
15:30 - 15:50 Coffee break
15:50 - 17:30 General assembly of the Society with drinks
18:30 - 20:00 Guided Walk through historic center of České Budějovice - – meet at the main square

Friday November 1, 2024

09:00 - 10:40 Session V (Chairperson: Petr Novák)
- 09:00 - 09:20 Stanislav Opekar
  FrO-17: The Longer, The Higher? ESI Responses of Model Oxo-Compounds labeled with Hydroxylamine Reagents Possessing Variable Alkyl Chain on a Quaternary Ammonium Moiety
- 09:20 - 09:40 Markus Wierer
  FrO-18: Non-Targeted Analysis of PFAS in Environmental Samples Using HPLC coupled with Drift Tube Ion Mobility and Quadrupole Time-of-Flight Mass Spectrometry
- 09:40 - 10:00 Martina Poncarová
  FrO-19: Products of photochemical degradation of the antidiabetic drug metformin
- 10:00 - 10:20 Gabriela Lokočová
  FrO-20: Bimodal imaging reveals a characteristic immune response to bacterial infection of the central nervous system
- 10:20 - 10:40 Klára Švihovcová
  FrO-21: Animal Behaviour Through the Lens of Mass Spectrometry
10:40 - 11:00 Coffee break
11:00 - 12:20 Session VI (Chairperson: Tomáš Pluháček)
- 11:00 - 11:20 Karel Hořejší
  FrO-22: Glycosphingolipidomics: Mass spectrometry profiling of glycosphingolipids in biological samples
- 11:20 - 11:40 Jan Šlauf
  FrO-23: MALDI MSI Reveals Brain Region-Specific Changes in Lipids as Mediators of Inflammation in an Experimental Model of Bacterial Infection of the Central Nervous System
- 11:40 - 12:00 Lucie Řimnáčová
  FrO-24: Quantification of Lipid Fatty Acids by Transmethylation, Isotope-Coded Derivatization and GC-PICI-MS Analysis
- 12:00 - 12:20 Joshua Smith
  FrO-25: Feature-Based Molecular Networking Guided Discovery and Isolation of Novel Capsaicinoids from the chili pepper (Capsicum sp.) and their TRPV1 activation
12:20 - 13:00 Poster prize, Final remarks
13:00 - 14:00 Lunch
14:00 - 17:40 Guided Tour to Hluboká nad Vltavou

List of posters:

WeP-01: Michal Kaleta: Targeted profiling of serum oxysterols by UHPLC–MS/MS
WeP-02: Jasmína Portašiková: DIGging into the DIGestion
WeP-03: Josef Dvořák: In-situ enrichment of serum proteins on functionalized immunoaffinity chips
WeP-04: Jiří Novák: Visualization of Secretion Kinetics in Microbes by CycloBranch
WeP-05: Anton Škríba: HILIC as an alternative separation method for RNA-caps and short oligonucleotides analysis
WeP-06: Dominika Olešová: Lipid dynamics in plasma and extracellular vesicles in the acute adaptive response to aerobic exercise
WeP-07: Michaela Myšáková: Comprehensive analysis of the redox proteome reveals survival pathways activated upon resistance to Pevonedistat
WeP-08: Tomáš Pluháček: Radiolarite artefacts provenance: multimodal elemental analysis
WeP-09: Volodymyr Pauk: Dyeing palette of Czech aristocracy from a mass spectrometric perspective – advantages and pitfalls of a comprehensive UHPLC-HDMS^E method
WeP-10: Filip Dyčka: Psychoactive Drug Effect on Fish Reproductive System: A Proteomic Perspective
WeP-11: Tomáš Smrčka: Hydrogen/deuterium exchange mass spectrometry for complex samples
WeP-12: Violetta Shestivska: Evaluation of MALDI-TOF MS and FTIR spectroscopy for typing of clinically relevant Acinetobacter baumannii clones isolated from hospital environments
WeP-13: Jakub Sinsky: Analysis of tau protein biology and interactome using crosslinking mass spectrometry
WeP-14: Petr Halada: Deciphering species diversity and trophic preferences of phlebotomine sand flies using MALDI-TOF mass spectrometry
WeP-15: Beata Pradlovská: Detection of human growth hormon using affinity MALDI mass spectrometry chips
WeP-16: Kristína Spustová: Optimization of the SPE Protocol for Oligonucleotide Sample Preparation
WeP-17: Michael Karpíšek: A novel cross-linking strategy for aromatic residues
WeP-18: Jana Knytlová: Detection of Selective Androgen Receptor Modulators and Anabolic-Androgenic Steroids in Dietary Supplements by Ambient Ionization Mass Spectrometry
WeP-19: Petr Vodrážka: Heptafluorobutyl Chloroformate Mediated Derivatization for Chiral Analysis of Secondary Amino Acids via GC-MS
WeP-20: Evgeniya Biryukova: Development of Software for LC-MS Data Processing of Oligonucleotides
WeP-21: Ivan Petřík: How electrospray tuning counteracts the matrix effect
WeP-22: Laura Zellner: HPLC-MS/MS method for simultaneous determination of six anti-cancer drugs in serum of lymphoma patients
WeP-23: Kateřina Jaklová: Subcellular fraction-specific interactomes of the tick-borne encephalitis virus capsid protein
WeP-24: Jana Havlíková: Middle-up quantification of infliximab in pharmaceutical matrix by capillary electrophoresis-mass spectrometry
WeP-25: Juraj Piestansky: Simple UPLC-MS amino acid analysis approach for quality control of KLH