CZechMS.org - CEEPC/IPM/CMSC 2022

CEEPC/IPM/CMSC 2022 - Program

Thursday September 29, 2022

8:30 - 10:00 Registration
10:00 - 10:10 Opening of the 16^th CEEPC, 8^th IPM and 10^th CMSC
10:10 - 11:00 Plenary lecture I: Karl Mechtler
PL-01: New insights through Single-Cell Proteomics
11:00 - 11:20 Coffee break
11:20 - 13:00 Session I - Method Development
- 11:20 - 11:40 Ondřej Vít
  ThO-01: Identification of potential cell-surface targets and druggable enzymes in human pheochromocytoma and paraganglioma using classical and membrane-targeting proteomic approaches
- 11:40 - 12:00 Petr Lapčík
  ThO-02: Global SEC-PCP-SILAC mapping reveals protein complexes mediating NF-κB activation in breast cancer
- 12:00 - 12:20 Haci Mehmet Kayili
  ThO-03: Determination of changes in the milk proteome in production and storage of kefir using mass spectrometry-based omics approaches
- 12:20 - 12:40 Katarína Maráková
  ThO-04: Non-Immunoaffinity Extraction of Intact Proteins from Biological Fluids and Their Analysis by Liquid Chromatography – Triple Quadrupole Mass Spectrometry
- 12:40 - 13:00 Adam Pruška
  ThO-05: Advancing Cyclic Ion Mobility Mass Spectrometry Methods for Studying Biomolecules: Towards the Conformational Dynamics of Mega Dalton Protein Aggregates
13:00 - 15:30 Lunch + Poster session I (Odd-numbered posters)
15:30 - 16:30 Workshop (Bruker Daltonics)
Gary Kruppa: The latest proteomics development at Bruker
Florian Meier: Clinical (phospho)proteomics with TIMS and PASEF
16:30 - 16:50 Coffee break
16:50 - 17:30 Short talks
- Josef Dvořák
  ThS-01: Detection of C. difficile Toxin B by biomolecule-modified chips and mass spectrometry
- Zuzana Kalaninová
  ThS-02: Optimized HDX-MS workflow for antibody structure monitoring by HDX-MS
- Denis Naplekov
  ThS-03: RPLC-UV and HILIC-UV characterisation of on-site produced Ramucirumab-DTPA immunoconjugate
- Agnes Revesz
  ThS-04: Collision energy setting in proteomics and glycoproteomics: From individual species to a practical perspective
- Matěj Běhounek
  ThS-05: Novel circulating biomarkers of biventricular heart failure
- Dana Dobešová
  ThS-06: Comprehensive metabolomic and lipidomic study of tauopathy and Alzheimer's disease patients
- Roman Tuzhilkin
  ThS-07: Overlooked oligomerization process in Azurin, a model metalloprotein
17:30 - 18:00 Josef Chmelik Award
18:00 - 19:30 Transfer to the quay
19:30 - 23:00 Conference dinner and sightseeing boat trip

Friday September 30, 2022

8:50 - 9:40 Plenary lecture II: Carlos Cordeiro
PL-02: An FT-ICR-MS metabolomic journey
9:40 - 11:20 Session II - Novel Instrumentation and approaches
- 9:40 - 10:00 Alan Kádek
  FrO-06: In a flash of light: Native mass spectrometry for single particle imaging with X ray free electron lasers
- 10:00 - 10:20 Volker Kruft
  FrO-07: Qualitative and quantitative advancements of QTOF performance: the SCIEX ZenoTOF 7600 system
- 10:20 - 10:40 Suresh Jivan Gadher
  FrO-08: Synergistic success of proteo-genomics in profiling human tear fluid for disease biomarkers using a novel high sensitivity Immunoassay
- 10:40 - 11:00 Stanislav Kukla
  FrO-09: Back to Basics with Antibodies
- 11:00 - 11:20 Maria van Agthoven
  FrO-10: Two-dimensional mass spectrometry for top-down analysis and structural characterization of proteins
11:20 - 11:40 Coffee break
11:40 - 13:00 Session III - MS and SW tools
- 11:40 - 12:00 Florian Meier
  FrO-11: Rapid ion mobility-resolved phosphoproteomics with dia-PASEF
- 12:00 - 12:20 Tomáš Ječmen
  FrO-12: Prediction of Intact N-Glycopeptide Retention Time Windows in Hydrophilic Interaction Liquid Chromatography
- 12:20 - 12:40 Jiří Novák
  FrO-13: Quantification of small molecules in liquid chromatography/mass spectrometry datasets by CycloBranch
- 12:40 - 13:00 Lászlo Drahos
  FrO-14: Mass spectrometric analysis of intact proteins: the dark side of deconvolution
13:00 - 15:30 Lunch + Poster session II (Even-numbered posters)
15:30 - 17:30 Session IV - Applications in Biomedicine 1
- 15:30 - 15:50 Katarina Davalieva
  FrO-15: Identification of potential biomarkers for azoospermia by human testis proteomic analysis
- 15:50 - 16:10 Pavel Bouchal
  FrO-16: Proteotype classification of renal cell carcinoma for prognosis and therapy response
- 16:10 - 16:30 Jiří Houšť
  FrO-17: Stability Study of Triacetylfusarinine C and Gliotoxin in bodily fluids
- 16:30 - 16:50 Petr Halada
  FrO-18: MALDI-TOF mass spectrometry: A powerful method for blood meal identification in insect vectors
- 16:50 - 17:10 Durga Jha
  FrO-19: Characterization of glycosphingolipids in iPSC-derived cerebral organoids and its application in neurodegenerative disorders
- 17:10 - 17:30 Kristýna Pimková
  FrO-20: Redox resetting by modulation of redox sensor Kelch-like ECH-associated protein 1 restores leukemic cells sensitivity to Azacytidine
17:30 - 18:10 Zdeněk Herman Award presented by Resonance Foundation and presentation of the winning thesis
18:10 - 18:30 Coffee break
18:30 - 19:00 General assembly of the CSMS

Saturday October 1, 2022

8:50 - 10:50 Session V - Applications in Biomedicine 2
- 8:50-9:10 Martin Hubálek
  SaO-21: Proteomic Analysis of Hepatitis B Virus
- 9:10-9:30 Jakub Sýs
  SaO-22: The single amino acid substitutions in Mason-Pfizer Monkey Virus matrix protein modulate its proteolytic cleavage rate
- 9:30-9:50 Viorel-Iulian Suica
  SaO-23: Cardiac alarmins as residual risk markers of atherosclerosis under lipid-lowering therapy
- 9:50-10:10 Tomáš Oždian
  SaO-24: Cervical mucus – a non-invasive uterine biomarker source?
- 10:10-10:30 Darshak Gadara
  SaO-25: High-Throughput µLC-MS/MS Lipidomics of 3D In Vitro Disease Models to Investigate Lipid Dysregulation
- 10:30-10:50 Eva Csosz
  SaO-26: Multi-omics network analysis in atherosclerosis reveals mechanisms driving the progression towords complicated lesion
10:50 - 11:10 Coffee break
11:10 - 12:00 Plenary lecture III: Bernd Wollscheid
PL-03: Light-mediated discovery of surfaceome nanoscale organization and inter-cellular receptor interaction networks
12:00 - 12:20 Poster prize, Closing remarks
12:20 - 13:30 Lunch

List of posters:

ThP-01: Lukáš Kučera: A mixture of innate cryoprotectants is key for freeze tolerance and cryopreservation of a drosophilid fly larva
FrP-02: Martina Opetová: Development of on-line pretreatment methods for growth factor analysis using CZE-MS
ThP-03: Eliška Ivanovová: LC-MS/MS Analysis of Short-Chain Fatty Acids and Their Derivatives in the Plasma of Women with Gestational Diabetes Mellitus
FrP-04: Alena Meledina: Determination of animal origin of recent and archaeological bones by mass spectrometry
ThP-05: Marek Vrbacký: Complexome profiling of mitochondrial OXPHOS knockout models
FrP-06: Jana Havlíková: Optimisation of middle-up HPLC-MS and CE-DAD approaches for infliximab quantification in therapeutic drug monitoring
ThP-07: Tereza Matysková: Wolffia australiana - a new perspective model for plant proteomics?
FrP-08: Radovan Tomašovský: Development and optimization of CZE-MS method for the analysis of selected growth factors
ThP-09: Aleš Marek: Tandem Mass Spectrometry of DNA Codons: From Cations to Cation Radicals
FrP-10: Siddharth Jadeja: The use of mobile phase with a low formic acid concentration in LC-MS proteomic analysis leads to enhanced electrospray ionization and improved sensitivity
ThP-11: Hynek Mácha: Maximizing peptide yield in biological sample preparation for LC-MS analysis
FrP-12: Jana Nádvorníková: Pea Seed Metabolite Profiling Using Combined GC/MS and PyGC-MS Analysis
ThP-13: Veronika Berková: Use of endophytic fungus in mitigating of cadmium toxicity
ThP-15: Juraj Piešťanský: Analysis of immunogenic peptide in vaccine formulation by a CE-MS approach
FrP-16: Rudolf Kupcik: High-Coverage Proteome Analysis of Rabbit Heart Samples Using 2D Conventional-Flow LC-MS
ThP-17: Jakub Červenka: Proteomic analysis of extracellular vesicles from porcine seminal plasma - Search for fertility markers
FrP-18: Mikuláš Vlk: Ion Mobility Mass Spectrometry Analysis of Aβ42 Oligomers
ThP-19: Tatiana Smirnova: Multi-omics approach to a comprehensive analysis of blood plasma for clinical diagnostics of hepatocellular carcinoma
FrP-20: Luminita Ivan: Residual hyperlipidemic stress under lipid lowering treatment may lead toward irreversible NAFLD
ThP-21: Miroslav Berka: The Omics Hunt for Novel Molecular Markers of Resistance to Phytophthora infestans
FrP-22: Petr Vodička: Comparison of SWATH-MS data analysis pipelines on proteomic data from human Huntington’s disease iPSC and NSC lines
ThP-23: Jianan Lu: Phospho-proteomic Analysis to Explore the Microbe Associated Molecular Patterns (MAMPs) in Plant Immunity
FrP-24: Romana Kopecká: Putative role of Plasmodiophora brassicae HSP70 in Arabidopsis thaliana and Brassica napus infection
ThP-25: Violetta Shestivska: Using MALDI-TOF MS for the detection of putative new Acinetobacter species from cattle feces
FrP-26: Marek Kalanin: Assessment of the effect of pretreatment of birch bark by supercritical extraction (scCO₂) with the following Soxhlet extraction: semiquantitative analysis of compounds by GC/MS
ThP-27: Konrad Kamil Hus: Proteomic and immunochemical characterization of Naja mossambica venoms from different geographical regions of Africa
FrP-28: Elena Uyy: Arterial Vessel Wall Proteome Alteration Involved in the Regulation of Cell Death Mechanisms in Atherosclerosis
ThP-29: Pavel Hruška: Adipocyte and adipose tissue proteome signatures in obesity
FrP-30: Aleš Kvasnička: Development of a novel approach for apocrine sweat microsampling and its utilization in breast cancer screening using pseudotargeted lipidomics
ThP-31: Marta Vlková: Proteomic analysis of heart tissue – study of amyloidosis
FrP-32: Volodymyr Pauk: Machine learning classification unveils secrets of natural indigo analyzed by ion mobility coupled to mass spectrometry
ThP-33: Josef Kucera: HDX-MS study of the HDM2 protein interaction with the Nutlin-3 compared to p53 protein
FrP-34: David Straka: Authenticity of animal furs using proteomics
ThP-35: Břetislav Brož: Identifying of Singly and Doubly Protonated DNA Trinucleotide Codons Using a Gas-Phase Dissociation
FrP-36: Aleksandra Bocian: 5 years of delving into the Naja ashei venom proteome
ThP-37: Ondrej Štefánik: Development and validation of a high throughput CZE-MS/MS method for sensitive quantification of triptorelin in pharmaceutical and biological matrices
FrP-38: Rita Sucha: Targeted mass spectrometry to identify optimal culture conditions for neural differentiation
ThP-39: Petra Krejčí: Potential of ASAP-MS Technique and its Application for Metabolite Profiling in Plant Microsamples
FrP-40: Barbora Piskláková: LC-MS/MS determination of direct oral anticoagulants in plasma of lupus positive patients
ThP-41: Jasmína Portašiková: Insights into the transport dynamics of prokaryotic chloride/proton antiporter
FrP-42: Helena Kupcova Skalnikova: Cytokine expression in spontaneous regression of melanoma in Melanoma-bearing Libechov Minipig model
ThP-43: Adéla Pravdová: Development of A Method For Lipopeptide Separation Using Liposomes
FrP-44: Anton Škríba: Mass spectrometry – based identification of 5’-RNA caps