CEEPC/IPM/CMSC - Abstrakt prezentace

(CEEPC/IPM/CMSC 2022 - FrO-09)
Back to Basics with Antibodies

Stanislav Kukla 1 *

  1. Merck Life Science spol. s r.o.

Abstrakt

In this sponsor talk, a couple of selected overlapping areas between proteomics research and mass spectrometry (MS) techniques will be highlighted and shown on antibodies and their manufacturing, characterization and usage in various antibody-based techniques as examples. You will learn about enhanced antibody validation during which new strategies and recently developed technologies are being used (including MS techniques) as a concept to bring more reproducibility and predictability to Life Science. Part of the talk will be also dedicated to describing different LC-MS approaches for middle-up, intact mass, glyco-profiling and peptide mapping analysis of protein therapeutics, such as monoclonal antibodies (mAbs). All discussed topics will be illustrated by our in-house R&D data that helped develop all the new reagents and tools that will be presented.

* Korespondující autor: stanislav.kukla@merckgroup.com


Partneři společnosti

LabRules LCMS LabRules GCMS

Partneři

Bruker HPST Merck Pragolab Amedis EastPort Shimadzu Waters