13. konference ČSHS a 11. Neformální proteomické setkání (joint meeting) - Program
Středa 19. listopadu 2025
- 10:00 - 18:00 Registrace
- 12:45 - 13:45 Oběd, jídelna - Biologické centrum AVČR
- 13:45 - 14:00 Zahájení konference
- 14:00 - 15:00 Plenary Lecture I: Prof. Alexander Makarov (Thermo Fisher Scientific) (Chairperson: Zdeněk Kukačka)
PL-01: Past, present and future of Orbitrap Mass Spectrometry - 15:00 - 16:00 Sekce I (Chairperson: Michael Volný)
- 15:00 - 15:20 Elliott James Price
WeO-01: Towards MS-guided Precision Environmental Health: the Czech node of the European Research Infrastructure for Human Exposome Research - 15:20 - 15:40 Urban Jiří
WeO-02: Optimization of microflow LC-MS method by design of experiments and its application to proteomics analysis - 15:40 - 16:00 Starovoit Mykyta
WeO-03: Simultaneous mapping of peptides and released N-glycans by HILIC-FLD-MS for quality control of protein biopharmaceuticals
- 15:00 - 15:20 Elliott James Price
- 16:00 - 16:30 Přestávka na kávu
- 16:30 - 16:50 Sponzorská přednáška – Phenomenex
Lucia Geis-Asteggiante: Advancing Nano/Micro LC Proteomics with Core-Shell Technology - 16:50 - 18:10 Sekce II (Chairperson: Jana Havlíková)
- 16:50 - 17:10 Melikov Aleksandr
WeO-04: G-quadruplex – ligand interaction biophysics explored by native mass spectrometry and trapped ion mobility spectrometry - 17:10 - 17:30 Smrčka Tomáš
WeO-05: Insights into CyRepA2 primase-helicase-DNA interactions using structural mass spectrometry - 17:30 - 17:50 Hájek Jan
WeO-06: Breaking the Unbreakable: Structural Elucidation of the Hypermodified RiPP Nostatin A by IRMPD Mass Spectrometry - 17:50 - 18:10 Portašiková Jasmína
WeO-07: Unraveling Oligomerization-Mediated Inhibition in GGPPS by Structural Mass Spectrometry
- 16:50 - 17:10 Melikov Aleksandr
- 18:10 - 18:30 Sponzorská přednáška – Genetica
: A Multi-Approach Exploration of the Proteome: Integrating Three Platforms - 18:30 - 19:00 Flash Talks I (Chairperson: Zdeněk Spáčil)
- Hebesberger Philipp: Quantification of Oxoacids of the Human Metabolome using Liquid Chromatography-Mass Spectrometry (WeS-01)
- Škeříková Veronika: Analyses of human scent samples (WeS-02)
- Grepl Jakub: rDUVLAESCI-MS/MSI: a novel approach for direct analysis of biological surfaces (WeS-03)
- Jágr Michal: Investigation of phenolic compounds in grape pomace through UHPLC-ESI-MS/MS (WeS-04)
- Brigante Federico: Mass Spectral Library Network (MERLIN) To Streamline The Generation Of Public Spectral Libraries (WeS-05)
- Mazumdar Aninda: A Comprehensive timsTOF MS/MS Spectral Library for Improving Metabolite Annotation in Non-Targeted Metabolomics (WeS-06)
- 19:00 - 22:00 Raut (jídelna, živá hudba od 19:30)
Čtvrtek 20. listopadu 2025
- 09:00 - 09:40 Workshop Pragolab
- 09:40 - 10:40 Sekce III (Chairperson: Tomáš Oždian)
- 10:40 - 11:00 Sponzorská přednáška – Amedis
Tomáš Korba: SCIEX ZenoTOF 8600 – Sensitivity, Speed, Flexibility, Robustness - 11:00 - 11:30 Přestávka na kávu
- 11:30 - 12:10 Workshop Genetica
Barry Ewen: Quantum-Si: Advancing Proteomics: an introduction to NGPS - 12:10 - 13:10 Sekce IV (Chairperson: Marek Vrbacký)
- 12:10 - 12:30 Černý Martin
ThO-11: Development-dependent molecular strategies of stress adaptation in plants - 12:30 - 12:50 Danchenko Maksym
ThO-12: Deciphering adaptive shifts in the redox proteome of wheat seedlings under drought - 12:50 - 13:10 Lochmanová Gabriela
ThO-13: No Mark, No Problem: Alternative Epigenetic Silencing in Algae
- 12:10 - 12:30 Černý Martin
- 13:10 - 14:00 Oběd
- 14:00 - 14:50 Plenární přednáška II: Prof. Bernhard Küster (Technical University of Munich) (Chairperson: Juraj Lenčo)
PL-02: Proteomics advancing pharmacology - 14:50 - 15:40 Flash Talks II (Chairperson: Petr Novák)
- Lenčo Juraj: Propionic acid boosts sensitivity in high-flow RPLC-MS proteomics compared to formic and acetic acid (ThS-07)
- Oždian Tomáš: Towards Biomarker Discovery: Multiomics analysis of Endometriosis (ThS-08)
- Šimoník Jan: Integrated proteogenomic analysis identifies synuclein gamma as a key target of the mesenchymal stem-like subtype of triple negative breast cancer (ThS-09)
- Vít Ondřej: Human IMPs: A tool for comparing outputs of different tools for transmembrane segment predictions in the human proteome (ThS-10)
- Lapčík Petr: LC-MS/MS-based terminomics unravels role of carboxypeptidase B1 in luminal A breast cancer (ThS-11)
- Sysel Jakub: Mass spectometry in hands of experimental biology: Impaired nucleotide salvage affects de novo synthesis in Drosophila melanogaster (ThS-12)
- Hinterholzová Helena: Bioaccumulation of pharmaceuticals in herbivorous fish: The role of aquatic plants as a dietary source (ThS-13)
- Koudelka Štěpán: LC-HRMS for large-scale chemical exposure studies (ThS-14)
- 15:40 - 17:00 Posterová sekce + přestávka na kávu
- 17:00 - 17:40 Workshop Bruker
Gary Kruppa: Recent developments in proteomics instrument at Bruker: timsTOF AIP and timsOmni for ultra high sensitivity proteomics, PTM analysis and structural proteomics
Daniel Vláčil: timsMetabo™ Breakthrough 4D-Metabolomics and 4D-Lipidomics Sensitivity, Specificity and Annotation Confidence - at Speed, Depth, and Scale - 17:40 - 18:00 Přednáška vítěze Ceny Josefa Chmelíka (Chairperson: Pavel Bouchal)
- 18:00 - 18:20 Schůze ČSHS, přednášková místnost
- 18:00 - 18:20 Neformální setkání Proteomické sekce ČSBMB, posterová místnost
- 19:00 - 22:00 Slavnostní večeře – Restaurace Solnice
- 21:00 Volitelná prohlídka Českých Budejovic s průvodcem – od Solnice
Pátek 21. listopadu 2025
- 09:00 - 09:50 Plenary Lecture III: Prof. Jana Roithová (Radboud University) (Chairperson: Anton Škríba)
PL-03: Mass Spectrometry access to quantitative solution kinetics - 09:50 - 10:50 Sekce V (Chairperson: Kristýna Gloc-Pimková)
- 09:50 - 10:10 Grabicová Kateřina
FrO-15: Per- and polyfluorinated compounds (PFAS) in wild common bream - 10:10 - 10:30 Kučera Lukáš
FrO-16: Spatial mapping of 15N-labeled ammonia with MALDI-FTICR imaging in regenerating liver tissue: Re-directing of toxic byproduct into anabolic pathways - 10:30 - 10:50 Čechová Aneta
FrO-17: LC-ICP-MS analysis of anti-obesity peptides and their metabolites labeled with lanthanide mass-tag
- 09:50 - 10:10 Grabicová Kateřina
- 10:50 - 11:00 Sponzorská přednáška – Shimadzu
David Maxa: Advancing Structural Elucidation with Oxygen Attachment Dissociation (OAD) - 11:00 - 11:20 Přestávka na kávu
- 11:20 - 11:40 Sponzorská přednáška – Bruker
Gary Kruppa: Emerging applications of bottom up proteomics in clinical research - 11:40 - 13:00 Sekce VI (Chairperson: Volodymyr Pauk)
- 11:40 - 12:00 Stefani Tommaso
FrO-18: Advancing Gut Microbiome Metabolomics: A Derivatization-Based Approach - 12:00 - 12:20 Chalupský Karel
FrO-19: Mass Spectrometry in Drug Development: From Screening to Stability and Pharmacokinetics - 12:20 - 12:40 Kyjaková Pavlína
FrO-20: Mass spectrometry of human body odor: Signatures of psychophysiological states - 12:40 - 13:00 Coufalíková Kateřina
FrO-21: Population-scale human chemical exposomics by automated liquid-liquid extraction coupled to gas chromatography – Orbitrap mass spectrometry
- 11:40 - 12:00 Stefani Tommaso
- 13:00 - 13:10 Závěr konference, vyhlášení cen
- 13:10 - 14:00 Oběd
- 14:00 - 17:40 Prohlídka pivovaru Samson nebo jaderné elektrárny Temelím s průvodcem
Seznam posterů:
- WeS-01: Philipp Hebesberger
- Quantification of Oxoacids of the Human Metabolome using Liquid Chromatography-Mass Spectrometry
- WeS-02: Veronika Škeříková
- Analyses of human scent samples
- WeS-03: Jakub Grepl
- rDUVLAESCI-MS/MSI: a novel approach for direct analysis of biological surfaces
- WeS-04: Michal Jágr
- INVESTIGATION OF PHENOLIC COMPOUNDS IN GRAPE POMACE THROUGH UHPLC-ESI-MS/MS
- WeS-05: Federico Brigante
- Mass Spectral Library Network (MERLIN) To Streamline The Generation Of Public Spectral Libraries
- WeS-06: Aninda Mazumdar
- A Comprehensive timsTOF MS/MS Spectral Library for Improving Metabolite Annotation in Non-Targeted Metabolomics
- ThS-07: Juraj Lenčo
- Propionic acid boosts sensitivity in high-flow RPLC-MS proteomics compared to formic and acetic acid
- ThS-08: Tomáš Oždian
- Towards Biomarker Discovery: Multiomics analysis of Endometriosis
- ThS-09: Jan Šimoník
- Integrated proteogenomic analysis identifies synuclein gamma as a key target of the mesenchymal stem-like subtype of triple negative breast cancer
- ThS-10: Ondřej Vít
- Human IMPs: A tool for comparing outputs of different tools for transmembrane segment predictions in the human proteome
- ThS-11: Petr Lapcik
- LC-MS/MS-based terminomics unravels role of carboxypeptidase B1 in luminal A breast cancer
- ThS-12: Jakub Sysel
- Mass spectometry in hands of experimental biology: Impaired nucleotide salvage affects de novo synthesis in Drosophila melanogaster
- ThS-13: Helena Hinterholzová
- Bioaccumulation of pharmaceuticals in herbivorous fish: The role of aquatic plants as a dietary source
- ThS-14: Štěpán Koudelka
- LC-HRMS for large-scale chemical exposure studies
- ThP-01: Marek Vrbacky
- Complexome profiling workflow elucidates mitochondrial cytochrome c oxidase biogenesis
- ThP-02: Stanislav Opekar
- Amino Acid Profiling Across Diverse Biological Matrices Using the MetAmino® LC-MS Kit: Applications in Free and Peptide-Bound Amino Acid Analysis
- ThP-03: Alzbeta Nemeskalova
- Ambient MS for rapid screening of pharmaceutically active compounds: Off-the-shelf and lab-made ion sources
- ThP-04: Olha Lakhneko
- ADAPTIVE PROTEOME UNDERPINS DROUGHT TOLERANCE IN BREAD WHEAT DURING FLOWERING
- ThP-05: Volodymyr Pauk
- Transition from natural dyestuffs to synthetic colorants depicted by ion mobility-aided mass spectrometry
- ThP-06: Ulrika Malá
- Off-line GC-GC×GC-MS focusing on scent samples
- ThP-07: Adam Neuman
- Ambient Soft Landing Voltammetry: Tool for Electrode Modification and Molecular Redox Characterization
- ThP-08: Andrej Kovac
- Translational research aimed at improving heatstroke diagnosis
- ThP-09: Filip Gregar
- Tracing the Gravettian Stone Paths
- ThP-10: Petr Čičmanec
- Leaf discs as a suitable alternative for cell cultures in plant omics analyses
- ThP-11: Tomáš Pluháček
- Characterization of Nanoparticles in Mixtures by Taylor Dispersion Analysis Hyphenated to Inductively Coupled Plasma Mass Spectrometry
- ThP-12: Kateřina Kubátová
- Sub-cellular interacting partners of the tick-borne encephalitis virus capsid protein
- ThP-13: Jana Bellová
- Mass Spectrometry-Based Proteomic Profiling of Sugiyamaella lignohabitans Adaptation to Xylose as Carbon Source
- ThP-14: Jakub Červenka
- Proteomic Analysis of Acetylsalicylic Acid-Induced Changes in the Cellular, Secreted, and Extracellular Vesicle Proteome of Malignant Melanocytes
- ThP-15: Lada Fialová
- Apparatus for Protein Footprinting by Singlet Oxygen
- ThP-16: Filip Dyčka
- Insight into Hemoglobin Digestion Pathways of Sphaerospora molnari by Functional Proteomics
- ThP-17: Jana Knytlová
- High-flow HESI interface with point-focusing and enhanced desolvation
- ThP-18: Tereza Hrdinová
- Proteomics identifies the landmark protein expression difference among the established mutation-based clusters of human pheochromocytoma and paraganglioma. Protein profiles can verify or correct diagnostic classification.
- ThP-19: Mária Dobšovičová
- Application of LC–MS/MS and fluorescence-based assays in the evaluation of novel carbonic anhydrase inhibitors
- ThP-20: Jarmila Štěrbová
- Production of sialylated glycoproteins in Ixodes ricinus ticks and tick cell lines
- ThP-21: Jaroslav Galba
- Application of LC–MS-Based “Polaromics” in Biochemistry, Pharmacology, and Biomedicine
- ThP-22: Evgeniya Biryukova
- Development of Software for LC-MS Data Processing of Oligonucleotides
- ThP-23: Palina Ryzhaya
- Enhanced Bottom-Up Proteomics for Histone Peptidoform Profiling
- ThP-24: Daniel Smíšek
- Detection of deoxynivalenol in grain products by LC-MS
- ThP-25: Ivo Chamrád
- FAmOS versus Percoll: Advancing Organelle Isolation Efficiency and Proteomic Compatibility in Plant Research
- ThP-26: Jana Havlíková
- Quantification of monoclonal antibodies by middle-up capillary electrophoresis coupled to mass spectrometry
- ThP-27: Natálie Zemánková
- Integrative proteomic and hormonomic analysis of barley chloroplast mutant chlorina f2f2
- ThP-28: Petra Majerova
- Microplastics and the Blood–Brain Barrier: Mechanisms of Transport and Endothelial Response
- ThP-29: Marta Cruz
- Reactivity of Singlet Oxygen Toward Amino Acid Side Chains
- ThP-30: Alina Sadchenko
- Applied and Residual: Assessment of Pesticide Residues and Transformation Products in Irrigated Czech Agricultural Fields.
- ThP-31: Michael Karpíšek
- Expanding the FFAP protocol for structural characterization of membrane proteins
- ThP-32: Zuzana Kalaninová
- DigDig: Streamlining Digestion Analysis for Proteomics and HDX-MS
- ThP-33: Ezgi Gurler
- Illuminating Proteins: Dual UV/IR Photodissociation in a custom FT-ICR system
- ThP-34: Michaela Myšáková
- Decoding Therapy-Induced Protein Subcellular Relocalization in Leukemia
- ThP-35: Dmitry Loginov
- Advancing AI/ML-Based Post-Translational Modification Assignment Using a Verified FPOP Dataset
- ThP-36: Petr Zacek
- Analysis of glycerophospholipids using the method of direct infusion into a tribrid mass spectrometer with high mass resolution
- ThP-37: Chao Zhang
- In situ comparison of hormonomics changes in different biotic stresses using mass spectrometry imaging
- ThP-38: Katerina Kucerova
- Large-scale metabolomics screening of understudied plant lineages
- ThP-39: Dušan Nemes
- Quantitative and Redox Proteomics Identify Signaling Networks Shaping Leukemia Survival and Resistance
- ThP-40: Petr Halada
- Deciphering phlebotomine sand fly taxonomy using MALDI-TOF MS protein profiling
- ThP-41: Haya Alsulaiti
- Metabolomics Analysis of Type 1 Diabetes Mellitus Among Qatari Children Using LC-MS
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